Certain molds like Aspergillus produce mycotoxins which directly damage mitochondria. Succinic acid has an important role in energy production [89]. Note that each number in parentheses [1, 2, 3, etc.] This process is known as the anaerobic (= without oxygen) metabolism of glucose. It is an NDMA receptor agonist, which is linked to various mental health disorders (anxiety, depression, suicidal ideation) and chronic neurodegenerative diseases (Alzheimers, Huntingtons). Fatty acid breakdown may serve as an important source of energy in periods of stress such as fasting, strenuous exercise, illness, especially in the heart, skeletal muscles, and liver [179, 180]. Many people struggle with low energy, and the OAT test can help uncover the root cause. My wife, though, must take PQQ post-exercise or she struggles with post-workout soreness for days even though we did a simple bike ride or hike. The oxalates may have specific clinical relevance to anyone suffering from recurrent kidney stones, as high levels of oxalic acid are a vital risk factor in kidney stone development. Trans-aconitic acid, on the other hand, is found in plants such as sugar cane [159]. Apart from its role in energy metabolism, pyruvic acid is also an antioxidant and helps decrease inflammation [2]. . A simple urine sample can be used to simultaneously assess the function and health of the Intestine, Liver, Nervous System, Energy Metabolism, Mitochondrial health as well as deficiencies in various nutrients. Clin Chem 41:1094-1104, 1995. Urinary p-cresol in autism spectrum disorders, Neurotoxicol Teratol. Clues into a possible metabolic inhibition or block due to a nutrient deficiency, an inherited enzyme deficit, toxic build-up, or a drug effect. On the flip side, your heart cells work very hard and have a ton of mitochondria. Some candida toxins can create problems with brain function, including memory, attention, and focus. Elevated markers in the neurotransmitter section can indicate toxic stress in the brain and nervous system. Ive been utilizing this test for over 21 years as it offers you so much information about how your body is functioning and where the imbalances are to reset so you can reach total wellness of mind and body. Prior to export from the nucleus, a 5' cap (red) and a 3' poly(A) tail (black) are added to help stabilize the mRNA and prevent its degradation by ribonucleases. A pack of 5 cost me $45 so $9 each. Seek immediate medical attention for high levels. The test checks for. It is one of the intermediate compounds our body uses to convert food into energy [1]. Your email address will not be published. Tags: ASD test, B vitamins, bacterial and yeast metabolites, Chronic Pain, Doctor's Data, fatigue, Functional Medicine, Genova Lab, GI Issues, Great Plains Lab, health, Healthy Living Everyday, lab testing, markers for vitamin and mineral levels, medical detective, mental health, Nancy Guberti, neurotransmitter test, neurotransmitters, nutrition, OAT, organic acid test, organic acids, oxalates, stress, total wellness, Total Wellness Empowerment, urine test, Vitamin C, Wellness. The organic acid arabinose is linked to this process of mucosal invasion. A key question to ask is: Which cell has the most mitochondrial density? The retina has the greatest metabolic demand and mitochondrial density in the body and displays progressive age related inflammation and marked cell loss.. to check if you have a deficiency in a specific nutrient. Required fields are marked *. Mitochondria are also damaged by oxalate, which is produced by Candida and some molds, and is also measured with organic acids testing. Nutrient recommendations for crucial vitamins, minerals, and digestive support, Functional pillars to guide treatment around needs for methylation support, toxic exposures, and mitochondrial dysfunction, A dynamic explanation for a more precise understanding. In the presence of these chronic stressors, tryptophan conversion to serotonin is reduced. | No comments. Organic acid test (OAT) has gained popularity among many functional health experts in recent years. The Organic Acid Test is overall more sensitive for candida analysis because it detects the chemical production in the digestive system that is reflective of these organisms metabolic activity and tissue invasion along the mucosal lining of the gut. Organix is a nutrition test that requires a first morning void (FMV) urine collection to measure organic acids. We follow the terms of this Notice. PQQ at times if I over-train but this rarely happens. Organic acids testing is diagnostic tool that every healthcare practitioner should know about. This profile assesses major metabolic areas that may be compromised by common lifestyle and dietary factors, such as nutrient deficiencies, toxicity, bacterial overgrowth, or medications. This often happens during exercise, for example. They also increase due to various other health issues. Follow all instructions in the test kit when you receive it. However, OAT has been increasingly available as a pricy, direct-to-consumer test recommended by many alternative practitioners. Among all of the markers reviewed above, there are three tests that doctors may actually use, depending on your signs, symptoms, medical history, and other test results: If your levels on any of the tests are abnormal, work with your doctor to find out why and treat any underlying health issues. Furthermore, glutathione deficiency can compromise ones immune system health and liver health since it is a necessary factor involved in supporting the liver to detoxify chemicals. Hope this information serves you well and helps you reach your genetic potential! SelfDecode 2013 2022 All Rights Reserved. Work with your doctor to find out whats behind abnormal levels and treat any underlying condition. A defect in a particular pathway can result in either accumulation or lowered levels of its byproducts. Suberic, sebacic, and adipic acid increase in rare metabolic disorders and vitamin B2 deficiency. You must log in or register to reply here. The Organic Acid Test examines metabolites found in a patient's urine that are byproducts and intermediates of cellular and gut microbiome metabolism . Clinical Practice of Alternative Medicine: 15-26. Now I can only lie on the bed 24/7, after any physical exertion, my strength becomes even less and the brain begins to think worse. Can you help me? Joe Cohen won the genetic lottery of bad genes. Information is shared for educational purposes only. They also are very fragile and susceptible to damage. This is an interesting article about the author's discovery of her less-than-effective ATP and mitochondrial issues, similar to what Dr. Myhill of the UK describes in her own articles, though Myhill uses CFS/Chronic Fatigue Syndrome as a label for mitochondrial problems. Persico AM, et. Glycolysis is the first step in glucose metabolism (breakdown of sugar) producing pyruvate and some energy (ATP). Breaking Down the 12 Sections of the Organic Acid Test The organic acid test evaluates biomarkers relevant to a range of health issues. In addition, the increased levels of oxidative stress and metabolic dysfunction may ultimately contribute to dysfunctional oxalate metabolism, leading to higher oxalic acid excretion. This can happen due to: Again, with so many factors affecting succinate levels, its important you work with your doctor to zero in on the underlying cause. Before exercising or post-exercise and commonly both I will use a, If I am absolutely trashed in the morning meaning I grunt, groan and dont want to get up at all I use. Any elevations in your organic acids can reflect a functional need for specific nutrients on a cellular and biochemical level, even despite normal blood levels. Subscribe to receive news, blogs, webinars, and updates, Assessment of Antifungal Drug Therapy in Autism by Measurement of Suspected Microbial Metabolites in Urine with Gas Chromatography-Mass Spectrometry. The test checks the organic acids, compounds formed during metabolic processing from the digestion of dietary protein, fat, and carbohydrates. Understanding how these individual systems work at . They can also decrease due to some underlying health conditions and medication. Some cells have more mitochondria than others. Checkout the markers the Organic Acid Test offers for you to reach total wellness. Any impairment in any step due to genetic or environmental factors can, in theory, lead to higher or lower levels of organic acids. markers since they can contribute to high cholesterol, weight mgmt issues, and mitochondria dysfunction. These markers reflect the bodys ability to process dietary macronutrients to feed the Krebs cycle and energy production. Many patients with autism also have mitochondrial dysfunction and chronic infections (like Candida and clostridia), which are measured with organic acids testing. Lactic acid gets broken down in the liver and kidneys and can accumulate in the body when it is produced faster than it can be removed [19, 20]. Finally, D-2-HG reduced the viability of H9c2 cardiac myoblasts, as determined by the MTT test and by propidium iodide incorporation. Our cells produce malic acid as an intermediate compound of energy metabolism [178]. This step takes place in the absence of oxygen. How Organic Acids Testing Works It can reveal imbalances in metabolic pathways, nutritional imbalances, mitochondrial dysfunction, urea cycle imbalance, oxidative stress as well as abnormal gastrointestinal microbial dysbiosis and malabsorption in the small and large intestines. Near infra-red increases ATP, Lichen Planus Treatment? Methylsuccinic acid, or methylsuccinate, is an intermediate metabolite in the breakdown of fatty acids. An organic acids testin a nutshellevaluates the organic acids that are excreted in your urine, to get a metabolic picture of your overall health. [tab] The Mitoswab test can identify current mitochondrial function of Complex 1 and IV. Want help making sense of your lab results? al. Citric acid also gets produced as a part of the energy metabolism in mitochondria. Kidneys are responsible for removing citric acid from the blood, either by breaking it down or by filtering it into the urine. The Organic Acid Test is a comprehensive assessment for a wide variety of biomarkers related to yeast (candida) and bacteria toxicity - specifically clostridia bacteria. Elevated tryptophan metabolites can lead to increased quinolinic acid (QA). As a health professional, I opened an account and bought 5 tests so I can run them on myself and my family. Where else can you obtain many clues on multiple aspects of ones physiology? It describes our legal duties, privacy practices and your patient rights as determined by the Health Insurance Portability and Accountability Act (HIPAA) of 1996. Without adequate mitochondrial function, neurons cannot function appropriately to produce neurochemicals such as dopamine and serotonin. These markers provide insight into health conditions and potential therapeutics to correct mitochondrial dysfunction. An essential maker and rarely checked isGlutathione. Urinary organic acids typically tested that involve the mitochondria include: Alpha-ketoglutarate ( 77) Cis-aconitate ( 78) Citrate ( 79) Fumarate ( 80) Elevations lead to recommendations to identify the vulnerabilities and minimize or remove them. The Great Plains Laboratory, LLC8400 W 110th Street, Suite 500Overland Park, KS 66210. The Organic Acid Test includes a section . Who Should Do The Organic Acids Test? Before I get there, lets addressa few things. We believe that the most accurate information is found directly in the scientific source. Its important for making proteins and decreasing protein breakdown in bones and muscles. The following hormones affect the kidney clearance of citrate [138]: These can decrease citrate levels in the urine: These increase your risk of having low citrate levels: Lower uric acid levels in the urine have been linked to kidney stones and osteoporosis [155, 156, 157, 158]. Since pyruvate levels can increase due to various causes, they are not particularly informative, unless they are used to check for rare metabolic disorders. Its used to check for RARE inborn genetic defects of metabolism, most often in newborns. The Organic Acid Test also known as the OAT test, specifically tests for organic acids - compounds in the urine that are produced during daily metabolism. Healthy food still tastes great just takes effort to make. Metabolism is a process that breaks down food to give you energy. When I learned about it, it was a clunky stick you held out in front of you with a card at the end. Its beneficial in pediatrics and adults since blood draws can be challenging and invasive to many. For a better experience, please enable JavaScript in your browser before proceeding. If you are struggling with mitochondrial dysfunction, I highly recommend doing the VCS Test along with looking for infections, stressors, environmental exposures and improving your digestion and sleep. Inborn errors of metabolism such as phenylketonuria and methylmalonic aciduria Key test in evaluation of individuals with If youve tried any of the above supplements, have they worked well for you? Seek immediate medical attention if your ketones are very high! Organic Acid Test is recommended for individuals with the following disorders: The Organic Acid Test is great forProactive and Preventative Planning for reaching total wellness of mind and body. Many things can affect the ability to perceive contrast. Les acidmies organiques apparaissent gnralement dans la petite enfance ou trs tt, provoquant une vaste gamme de symptmes. Did you know that certain strains of C. diff. As you exercise, use your eyes for work, lift heavy things or think hard throughout the day, your mitochondria are there helping you out by giving your cells ATP. These chemicals inhibit Dopamine-Beta Hydroxylase which causes neuronal dopamine levels to rise. What changed? Shaw, W., et. Brain. Since there are so many different things and conditions that can cause an increase in lactic acid, some of them life-threatening, its very important that you dont try to self-diagnose! Hello, I have had mitochondrial encephalopathy for more than 5 years, but not the same as usual. I dont have strokes or vision problems. I lack the energy to lead a fulfilling life. Pyruvic acid is created in the metabolism of carbs, proteins, and fats. We use your Protected Health Information for treatment, payment, or healthcare operations purposes and for other purposes permitted or required by law. The accumulation of specific organic acids detected in . The Organic Acid test metabolic sections are: These chemical reactions are the foundation of our physiologic system, and our health is dependent on their optimal functioning. I hope to see others post their OAT results here, as the mitochondrial problem can explain a LOT about someone's so-called "CFS" diagnosis. Your test results indicate that you were able to discern the tilt of the bars in the test images 84 times out of 90, for a Total Score of 84, or 93%. Quinolinic acid can also block acetylcholine production (linked to memory) and gamma-amino-butyric acid (which can trigger anxiety and panic). The report includes personalized micronutrient recommendations for vitamin and mineral cofactors as well as digestive support recommendations based on a patient's individual biochemical metabolism. We are dedicated to providing the most scientifically valid, unbiased, and comprehensive information on any given topic. Are all OAT tests different? Read on to find out which ones are actually worth testing. Mitochondria are the powerhouse of energy factories of our cells, acting as energy currency for our bodies. Several bacterial markers include the Clostridia bacteria, such as Clostridia difficile (C. Organic acid test (OAT) has gained popularity among many functional health experts in recent years. By what you are saying, it does sound like his Arup OAT test is different. N-Acetylcysteine is necessary as a precursor for the super important antioxidant glutathione. They are continually monitored by our internal peer-review process and if we see anyone making material science errors, we don't let them write for us again. All of our content is written by scientists and people with a strong science background. And I'm going to kind of pull up a sample report and go over the different categories of information that we gained from doing this particular test. recently my son had an OAT that shows all normal. Huge gains. A large part of the test looks at metabolites involved in energy production, including those involved in carbohydrate and fatty acid metabolism and mitochondrial markers. Int J Alzheimers Dis. I have been searching for information but the only things I read to withhold were vitamins. Contact Us | Terms of Service | Privacy & Security. Thats quite affordable and a great way to monitor treatment and also identify if you do have something going on. Elevated urine succinate levels are used to screen for rare metabolic disorders. We also found that this organic acid compromised mitochondrial Ca 2+ retention capacity in heart mitochondrial preparations and H9c2 myoblasts. Most of these markers are mainly used to diagnose rare genetic disorders, and there's likely . Fumaric and malic acid are used to screen for rare metabolic disorders. His hx of autism, CNS dysfunction, anxiety, hypotonia and depression have me searching for an imbalance that I may be able to strengthen. This includes laboratory test orders and test results as well as invoices for the healthcare services we provide. diff. . These markers check for folate, which is linked to the methylation cycle, supporting the functioning of cells related to DNA function and metabolism. Inadequate folate metabolism can lead to cognitive problems. The cycle consists of a series of reactions, with metabolites entering at various steps from other metabolic pathways [87]. Its a donation. Thus, measuring the levels of these markers can help to identify which metabolic process is blocked or compromised. Lactic acid in excess can lower the pH of the blood and cause what is known as lactic acidosis. OAT Great Plains 70 . It also evaluates oxalate toxicity, as well as mitochondria function, and various markers for vitamin and neurotransmitter problems. Read the article and judge for yourself. Lactic acid is produced in the body as cells convert food (glucose) into energy. Anticholinesterase and Antioxidative Properties of Aqueous Extract of Cola acuminata Seed In Vitro. 7. Ive been utilizing this test for over 21 years as it offers you so much information about how your body is functioning and where the imbalances are to reset so you can reach total wellness of mind and body. This lecture by Kurt N. Woeller, DO will explore this section of the OAT in more detail and discuss the clinical relevance of these markers. She was diagnosed with rheumatoid arthritis when she was 17. If I forget to take it for even one day I feel as though I have the flu extreme fatigue and less than 0 motivation. Last but not least, we look at severalNutritional Markersto check if you have a deficiency in a specific nutrient. But how informative are these markers? Amino Acids Metabolitesare included to help you know if you have a metabolic imbalance or an inborn error in metabolism. Ideally, you go to a skilled health professional who can identify mitochondrial dysfunction via history, physical exam, organic acid testing and a few other lab tests. Excess pyruvate has an escape route where it is converted to oxaloacetate and lactic acid [3]. Benefits of checking this test in people not suspected of having genetic disorders are unknown. Additionally, thyroid hormones and cortisol influence the Kreb cycle [88, 87]. A lactic acid test is often ordered when a person has signs of low oxygen (hypoxia) and lactic acidosis such as [19]: Higher lactic acid levels can be caused by many different factors and conditions, including: Severity and symptoms of lactic acidosis can vary widely depending on which metabolic pathway is not functional and can range from severe neurological degeneration in newborns (Leigh syndrome) and early death to relatively normal life with episodes of vomiting, nausea, and generalized weakness [86]. The benefits of checking these metabolites other than for testing for genetic disorders are not clear. al. The Organic Acids Test (OAT) offers a comprehensive metabolic snapshot of a patient's overall health with 76 markers. Neurotransmitter health is evaluated and crucial for helping with depression, anxiety, and chronic stress. We also know that those with diabetes tend to have more vision problems than those without. Side note I do have a double hit on my MTHFR. The test takes a closer look at, evaluate for these toxins linked to neurological and mental health issues. al. Mito. Do you want to get a snapshot of approximately 77 aspects of your metabolic and cellular health and detect alterations in the gut microbiome, vitamin deficiencies, levels of neurotransmitters, and exposures to mold or fungus? Again, this is a test used to screen for rare metabolic disorders, but levels may also increase in some other conditions. If the bacterial markersare elevated, it shows dysbiosis in your GI tract. If you have not tested your glutathione levels, you may miss out on a very important clue to achieving total wellness. Organic Acid Test, popularly known as OAT, measures the levels of organic compounds in urine that are produced in the body as a part of many vital biochemical pathways. It measures the function of the Citric Acid Cycle, which is how your body makes energy! helps you gain insight into your detoxification functioning. (1), Mitochondria are linked to every organ system in the body, including the brain, and there markers for mitochondrial function in organic acids testing. It will help identify the root causes of dysfunction and provide a science-based approach to help you overcome chronic conditions, gain insight into your functioning, and live healthier lives to reach total wellness of mind and body. Energy Production. Alpha-ketoglutarate, also known as alpha-ketoglutaric acid or 2-oxoglutaric acid, is an intermediary compound of energy metabolism. These can be life-threatening or quite severe a bit later in life. Tryptophan is the amino acid precursor to serotonin. Since the lab test is a urine test, it is straightforward for you to do it at home. Mitochondrial, Carb & Fatty Acid Metabolites. Levels can also increase due to various other health issues, which is why a doctor will interpret them together with other tests, your signs, symptoms, and medical history. is a clickable link to peer-reviewed scientific studies. . Some gut bacteria also produce lactic acid [19, 20]. These increase acetoacetic acid and BHB levels: Studies suggest that BHB levels gradually increase as we age [223]. What if I told you there is a way to do it online using your eyes? Alpha-ketoglutarate test is used to screen for rare metabolic disorders. Is the Weed Killer Glyphosate Harming Your Health? We are also required to provide you with this Notice upon request. Very high levels of gamma-hydroxybutyric acid indicate a genetic disorder, called succinic semialdehyde dehydrogenase deficiency (SSADHD) [260]. Levels can increase when enzymes that break down succinic acid dont work properly. It gets used and removed quite efficiently, and therefore the blood and urine levels are normally low [19, 20]. However, now we can use this advanced testing to assess many aspects of our health. Following the treatment regimen your doctor prescribes will help decrease lactic acid back to normal. Recharging mitochondrial batteries in old eyes. They are normally found in negligible amounts in blood and urine. Eat well vs processed tasty garbage food. Dans la plupart des cas, le test des acides organiques dans l'urine identifiera les concentrations de 63 substances diffrentes, qu'elles soient normales ou leves. Abnormal urinary organic acids, organic aciduria, is seen genetic disorders of amino acid metabolism, mitochondrial fatty acid beta-oxidation metabolism, and of mitochondrial oxidative phosphorylation metabolism. they suggest supplementing with glutathione may be beneficial. Candida and clostridia are both measured with organic acids testing. When one or more pathways are not functioning properly, organic acids will "overflow" into the urine. It is produced when cells convert food into energy [116, 117]. And if so for how long? When the mitochondria are stressed because of toxins from candida, bacteria, oxalate, heavy metals, and environmental chemicals, then dysfunction may occur. To find out which parts of the OAT test can be useful, and which are nonsense, we delve into the science and look into each of the marker types in isolation: Labs in the normal range does not always indicate optimal health. Succinic acid metabolism is also linked with heme synthesis, ketone bodies utilization, and the GABA shunt [90]. She spent 4 years reviewing the scientific literature on supplements, lab tests and other areas of health sciences. They are produced in the liver from fatty acids to be used as an energy source by other tissues in case of glucose/carbohydrate shortage [223, 224]. Not every use or disclosure is listed in this Notice, but all of our uses or disclosures of your health information will fall into one of the categories listed in our privacy practices. Other clostridia toxins work outside the digestive system, such as different strains of clostridia, HPHPA, and 4-cresol. Medium- and short-chain fatty acids are transported directly into the mitochondria, but long-chain fatty acids need carnitine to get transported across the mitochondrial membrane [179, 180]. Elevated oxalate is often associated with joint and muscle pain and bladder and bowel discomfort. The issue is in order to make ATP, your mitochondria have to be healthy and get the nutrients and components they need. Attenuation of synthesis from L-tryptophan by 6-chlorotryptophan and 4-chloro-3-hydroxyanthranilate. Comment below sharing what you do along with what has worked and what hasnt. Make your health a priority by gaining insight into your bodys functioning so you can work on any imbalances. I cleaned it all up. Fumaric acid is an intermediate compound produced in mitochondria as cells convert food to energy. Selfhacked LLC does not provide medical advice, diagnosis, or treatment. Gamma-hydroxybutyric acid (GHB), also called 4-hydroxybutyric acid, occurs naturally in the nervous system and can be found in trace amounts in the brain. Get Started. They also increase due to various other health issues, and can cause lactic acidosis, which is a life-threatening condition. Enzymes responsible for metabolizing organic acids are vitamin and mineral dependent, and these markers are included n the test. I am telling you that. document.getElementById( "ak_js_1" ).setAttribute( "value", ( new Date() ).getTime() ); This site uses Akismet to reduce spam. The Organic Acids Test (OAT) is a comprehensive test that gives metabolic insight into a person's overall health. Click here to read the full Notice of Privacy Practices. Biljana received her PhD from Hokkaido University. Lactic acid is a microbial metabolite, urinary lactic acid is produced by Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumonia, Enterobacter, Acinetobacter, Proteus mirabilis, Citrobacter frundii, Enterococcus faecalis . And what it is, is it uses a urine sample to get a bunch of metabolite data. Your test seems "short" also and has different metabolytes as well. Pyruvate, then, enters mitochondria and is converted into acetyl CoA, which is then metabolized in the Krebs cycle to produce more energy in the presence of oxygen. Our science team must pass long technical science tests, difficult logical reasoning and reading comprehension tests. The Mitochondrial Markers - Amino Acid Metabolites section of the OAT often shows elevated markers. Beta-oxidation, which occurs in the mitochondria, is the main pathway through which fatty acids generate acetyl-CoA, which is the fuel that allows the mitochondria to create usable energy (ATP). Before joining SelfHacked, she was a research scientist with extensive field and laboratory experience. I have tried quitting cold turkey and failed miserably! Mitochondria are the powerhouse of energy factories of our cells, acting as energy currency for our bodies. . A toxic compound is checked with the quinolinic acid marker. As a kid, he suffered from inflammation, brain fog, fatigue, digestive problems, anxiety, depression, and other issues that were poorly understood in both conventional and alternative medicine. One of the primary functions of the cycle is to generate NADH & FADH, which are utilized to produce energy (in the form of ATP) in the electron transport chain (ETC). If abnormal, work with your doctor to find the cause and treat any underlying condition! The, help determine your mitochondria (energy production part of the cell) functionality. If the bacterial marker is elevated, check if the neurotransmitter dopamine is as well since that combination can cause mood instability and cognitive issues. Now you can do this on your cell phone, laptop or desktop. This test is called the VCS Test which stands for Visual Contrast Sensitivity Test. There are many other tests that doctors can use to evaluate your overall health that are reliable and backed up by plenty of studies and actual science. Treatment may include the use of antioxidants and nutritional support for detoxification pathways. Indicators of Detoxification and Amino Acid Metabolites and Bone Metabolites were all normal range. It provides an accurate evaluation of intestinal yeast and bacteria. Referring to is gradual onset over a longer period of time, these high of Make ATP, your right visual system advanced testing to assess the levels lactic! The ability to process dietary macronutrients to feed the Krebs cycle intermediate can Bodies are functioning also very susceptible to damage [ 89 ] the author noted that while detoxing copper. Excessive hormones and proteins the brain and nervous system, which is how your body makes cis-aconitic acid an!, help determine your mitochondria ( energy production part of a series reactions. Purposes and for other purposes permitted or required by law to maintain the Privacy of your are. A closer look at, evaluate for these purposes are both measured with organic acids in to! 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