Risk factors for developing acute phosphate nephropathy include increased age, hypovolemia, renal impairment, bowel obstruction, or active colitis. ACTH . It should not be used with sodium-retaining medications. When sodium phosphate dibasic dissolves in water, the basicity is higher in the medium than when sodium phosphate monobasic dissolves in water. Intravenously infused phosphorus not taken up by the tissues is excreted almost entirely in the urine. is this? Apply now! Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Dissolve Sodium Phosphate (dibasic and monobasic) and Sodium Chloride in approx. https://dailymed.nlm.nih.gov/dailymed/labelrss.cfm?setid=e6169d3b-39d2-47f9-8d5b-b53ec069a722, https://dailymed.nlm.nih.gov/dailymed/rss.cfm. Blood and urine tests and an electrocardiogram (ECG) may be needed to check for unwanted effects. per page. One mM of phosphorus weighs 31 mg, and the product provides 93 mg (approximately 3 mM) of phosphorus/mL plus 92 mg (4 mEq) of sodium/mL. Corticosterone. Sodium phosphate dibasic and sodium phosphate monobasic should come with a Medication Guide. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. It is provided as 5 mL, 15 mL and 50 mL partial fill single-dose vial; when lesser amounts are required, the unused portion should be discarded with the entire unit. Taking more than one dose of over-the-counter (OTC) sodium phosphate medicine in 24 hours may cause serious kidney and heart problems. This Thermo Scientific brand product was originally part of the Acros Organics product portfolio. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit (see PRECAUTIONS). CAS: 7782-85-6: Molecular Formula: H17Na2O11P: Molecular Weight (g/mol) 270.08: MDL Number: MFCD00149180: InChI Key: PYLIXCKOHOHGKQ-UHFFFAOYSA-N: Synonym: sodium . Pricing displayed in catalog does not include applicable taxes. It exerts a modifying influence on the steady state of calcium levels, a buffering effect on acid-base equilibrium and a primary role in the renal excretion of hydrogen ion. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. The solution is administered after dilution by the intravenous route as an electrolyte replenisher. Monobasic Sodium Phosphate Monohydrate, 12 kg, 98 to 102% Assay, Baker Analyzed ACS Reagent Grade, CAS Number 10049-21-5, NaH2PO4.H2O Chemical Formula, 137.99 g/mol Molecular Weight, White, Crystalline Powder, 200C Melting Point, 204C Boiling Point Manufacturer Part #: 3818-07 Dibasic Sodium Phosphate, USP (anhydrous) is chemically designated Na2HPO4, colorless or white granular salt freely soluble in water. Caution must be exercised in the administration of parenteral fluids, especially those containing sodium ions, to patients receiving corticosteroids or corticotropin. Description. The dose and rate of administration are dependent upon the individual needs of the patient. When dissolved in solution, a single base group will neutralize the dissociated sodium atom. While the sodium ion can diffuse across cell membranes, intracellular sodium is maintained at a much lower concentration than extracellular sodium through the expenditure of energy by the cell (so-called sodium cation pump). muscle cramps in the hands, arms, feet, legs, or face. If your dose is different, do not change it unless your doctor tells you to do so. The normal level of serum phosphorus is 3.0 to 4.5 mg/100 mL in adults; 4.0 to 7.0 mg/100 mL in children. In patients on total parenteral nutrition, approximately 12 to 15 mM of phosphorus (equivalent to 372 to 465 mg elemental phosphorus) per liter bottle of TPN solution containing 250 g dextrose is usually adequate to maintain normal serum phosphorus, though larger amounts may be required in hypermetabolic states. These are more likely to occur if you are over 55 years of age, dehydrated, have low blood volume, and are taking medicines that could be hard on your kidneys (eg, diuretics or water pills, certain blood pressure medicines, NSAID pain or arthritis medicine). dry mouth. Some documentation and label information may refer to the legacy brand. Since these are salts, they readily dissolve in water and produce alkaline solutions. We comply with the HONcode standard for trustworthy health information. (Select up to 3 total.) It is often used as an additive in processed food manufacturing. However, cases have occurred in patients with no identifiable risk factors . On the other hand, adrenal secretion of aldosterone increases renal tubular reabsorption of sodium in an effort to re-establish normal serum sodium concentration. CLINICAL PHARMACOLOGY Medically reviewed by Drugs.com. 2. Get Label RSS Feed, It is also not known whether sodium phosphate can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Visicol(R): It is important to use the dose and dosing regimen as recommended (pm/am split dose).. Pay Less. lightheadedness. The vials marked with PX are partially filled to facilitate transfer of the contents. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy. The pH of this aqueous solution is a basic value, which is between 8 and 11. Sodium Phosphate, Monobasic, Monohydrate Chemical Formula: NaH 2 PO 4 H 2 O. Solubility: Soluble in water. Do not administer unless solution is clear and seal is intact. Files, Presentations Serum phosphorus levels should be regularly monitored and appropriate amounts of phosphorus should be added to the infusions to maintain normal serum phosphorus levels. This compound can be made when phosphoric acid reacts with a sodium salt like sodium halide. For further information about unapproved drugs, click here. One phosphorus atom is bonded with four oxygens, to form a -3 polyatomic anion. SpectraBase Compound ID: 7nGsjLSqiUI: . Examples of clear liquids include: water, flavored water, clear broth, herbal tea, black tea, coffee, clear soda, gelatin, popsicles, lemonade (no pulp), ginger ale, white grape juice, or apple juice. & Articles, All Select Attribute While it can be toxic, especially in combination with other drugs, sodium phosphate solutions help relieve symptoms of constipation. . Our team periodically reviews articles in order to ensure content quality. Keep from freezing. Calcium levels should be monitored. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. View NDC Code(s)NEW! Make sure your doctor knows if you had a heart rhythm problem, such as QT prolongation. A monobasic salt refers to a salt, which has only one atom of an univalent metal. The term monobasic refers to the neutralization of the molecule by a single or univalent base group. We comply with the HONcode standard for trustworthy health information. Discard unused portion. This is a decision you and your doctor will make. @media (max-width: 1171px) { .sidead300 { margin-left: -20px; } } The osmolar concentration is 7 mOsmol/mL (calc). By contrast, the dibasic form of sodium phosphate having the formula Na2HPO4 +2H2O, dissociates into two sodium atoms when dissolved, requiring two basic groups to neutralize them. Day of colonoscopy (starting 3 to 5 hours before the procedure): Four tablets with 8 oz. Copyright 2022 Leaf Group Ltd., all rights reserved. The solution is intended as an alternative to potassium phosphate to provide phosphorus for addition to large volume infusion fluids for intravenous use. Use with caution in patients with renal impairment, cirrhosis, cardiac failure or in conjunction with other edematous medications. The molar mass of the compound is 142 g mol-1. 1-877-567-3598 USD . The osmolar concentration is7 mOsmol/mL (calc.). The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific. Animal reproduction studies have not been conducted with sodium phosphate. Phosphorus is present in plasma and other extracellular fluid, in cell membranes and intracellular fluid, as well as in collagen and bone tissues. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Monobasic Sodium Phosphate, USP (monohydrate) is chemically designated NaH 2 PO 4 H 2 O, white, odorless crystals or granules freely soluble in water. This compound is also known as disodium phosphate and has the molecular formula of Na2HPO4. The study uses data from the FDA. Sodium Phosphates Injection, USP, 3 mM P/mL (millimoles/mL), is a sterile, nonpyrogenic, concentrated solution containing a mixture of monobasic sodium phosphate and dibasic sodium phosphate in water for injection. Negative reactions could result if taken in combination with drugs designed to lower blood pressure, treat depression, or manage pain, or if you are pregnant or breastfeeding, having kidney or heart or electrolyte problems or a history of seizures. Appearance: White or transparent crystals or granules. Phosphorus is present in plasma and other extracellular fluid, in cell membranes and intracellular fluid, as well as in collagen and bone tissues. Sodium phosphate dibasic and sodium phosphate monobasic may cause serious allergic reactions, including anaphylaxis and angioedema, which can be life-threatening and require immediate medical attention. Sodium phosphate monobasic is available as colorless crystals or white powder. The molar mass of the compound is 120 g mol-1. Drug class: Laxatives. The anion in this molecule is not the trivalent phosphate anion, but the H2PO4 anion. * Breathing Sodium Phosphate Dibasic can irritate the nose and throat causing coughing and wheezing. This will also keep your kidneys working well and help soften your bowel movements, making them easier to pass. Disodium phosphate Formula: HNa2O4P 7H2O Molecular weight: 268.07 g/mol CAS-No. The dose and rate of administration are dependent upon the individual needs of the patient. Mono Sodium Phosphate, as called Sodium Acid Phosphate, is used as a thickening agent and emulsifier in evaporated milk, as stabilizer in dairy products, meats and sea food, as additive in animal feed to improve. Your email address will not be published. Do not administer unless solution is clear and seal intact. DISCLAIMER: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. These two ions are in equilibrium with each other keeping cellular fluids in a tight pH range of about 6.9 to 7.4. Sodium is the principal cation of extracellular fluid. Composition: Sodium Phosphate, Dibasic, Heptahydrate 100% Grade: ACS Reagent CAS Number: 7782-85-6 Density: 1.7 Chemical Formula: Na2HPO4.7H2O Molecular Weight: 268.07 g/mol Melting Point: >240 C (decomposes) Color: Colorless/white solid Physical State: Solid pH Range: 8.7 to 9.3 Compare this item Adrenal. Sodium phosphate dibasic and sodium phosphate monobasic combination is used to clean or empty your bowels before an imaging procedure called colonoscopy. In the event of overdosage, discontinue infusions containing sodium phosphate immediately and institute corrective therapy to restore depressed serum calcium and to reduce elevated serum sodium levels. Sign-in or Create an Account Catalog Number SX0715. Phosphorus, present in large amounts in erythrocytes and other tissue cells, plays a significant intracellular role in the synthesis of high energy organic phosphates. Cell culture, genetics, proteomics, molecular biology, immunology, cell therapy, gene therapy, bioprocess, screening. Sodium phosphate dibasic and sodium phosphate monobasic may cause serious kidney problems. 119/ Kg Get Latest Price. So in the laboratory we can make this compound by reacting two equivalents of sodium hydroxide with one equivalent of phosphoric acid. Sodium Phosphate, Monobasic, Monohydrate General Characteristics. Do not keep outdated medicine or medicine no longer needed. When two sodium cations replace the hydrogen atoms in the phosphoric acid, sodium phosphate dibasic is obtained. loss of appetite. Do not eat solid food. Sodium Phosphate, Monobasic, Monohydrate, ACS, 5323 ; Revised on 09/27/2021 Page 6 of 6 ; Disclaimer: The information provided in this Safety Data Sheet ("SDS") is correct to the best of our knowledge, information, and belief at the date of publication. The compound is a white crystalline solid, and it readily dissolves in water. Sodium Phosphate, Monobasic, monohydrate: 0.386 g/L Sodium Chloride: 8.766 g/L Sodium Azide: 0.500 g/L 5M HCl: As needed 5M NaOH: As needed Distilled Water (dH2O) Directions 1. The anion in this molecule is not the trivalent phosphate anion, but the H 2 PO 4- anion. RxNorm, The information contained on this site is for informational purposes only, and should not be used as a substitute for the advice of a professional health care provider. PubMed, Research indicates that patients with impaired kidney function, including premature neonates, who receive parenteral levels of aluminum at greater than 4 to 5 mcg/kg/day accumulate aluminum at levels associated with central nervous system and bone toxicity. If you no longer wish to have this DailyMed RSS service, simply delete the copied URL from your RSS Reader. Tell your doctor right away if you have a rash, itching, hoarseness, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth after using sodium phosphate dibasic and sodium phosphate monobasic. high-purity dextran sulfate sodium (DSS). Use of medications that may impair renal perfusion or function may also increase risk. : 237-707- No components need to be disclosed according to the applicable regulations. (adsbygoogle = window.adsbygoogle || []).push({}); Copyright 2010-2018 Difference Between. It readily dissolve in water, but do not dissolve in organic solvents like alcohol. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific. Data sources include IBM Watson Micromedex (updated 1 Nov 2022), Cerner Multum (updated 25 Oct 2022), ASHP (updated 11 Nov 2022) and others. Labels, All Index generic drugs) are not considered. 0.1 M sodium phosphate buffer (pH 7.4) Add 3.1 g of NaH 2 PO 4 H 2 O and 10.9 g of Na 2 HPO 4 (anhydrous) to distilled H 2 O to make a volume of 1 L. The pH of the final solution will be 7.4. Dihydrogen phosphate or H2PO4- ions act as acids while the hydrogen phosphate or HPO4 ions act as bases. (see Following is the structure of phosphate anion. Most of these salts are known in both anhydrous (water-free) and hydrated forms. Material Safety Data Sheet or SDS for Sodium Phosphate, Dibasic, Heptahydrate SX0715 from MilliporeSigma for download or viewing in the browser. Sodium ions and phosphorus are known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function. This helps your doctor see the inside of your colon more clearly during the colonoscopy. And dibasic salt means having two univalent metal ions. Infusing high concentrations of phosphorus may result in a reduction of serum calcium and symptoms of hypocalcemic tetany. Sodium Phosphates Injection, USP, 3 mM P/mL in single dose vials, is supplied as follows: *The container is partially filled to provide air space needed for complete vacuum withdrawal of the contents into the IV container. Sodium Phosphates Injection is administered intravenously Phosphate intoxication results in a reduction of serum calcium and the symptoms are those of hypocalcemic tetany (see 2O. In patients with diminished renal function, administration of solutions containing sodium ions may result in sodium retention. +) ion. Contextual translation of "tri sodium phosphate" into Greek. Updated All rights reserved. Aluminum may reach toxic levels with prolonged parenteral administration if kidney function is impaired. Useful in conjunction with Sodium Phosphate, Monobasic in the preparation of biological buffers. Hypophosphatemia should be avoided during periods of total parenteral nutrition (TPN), or other lengthy periods of intravenous infusions. Tissue loading may occur at even lower rates of administration. increase in heart rate. L.To make a purchase inquiry for this buffer, please provide your email address below: Request quotation One mM of phosphorus weighs 31 mg, and the product provides 93 mg (approximately 3 mM) of phosphorus/mL plus 92 mg (4 mEq) of sodium/mL. The term monobasic refers to the neutralization of the molecule by a single or univalent base group. WARNING: This product contains aluminum that may be toxic. Sodium phosphate monobasic and sodium phosphate dibasic are two other compounds of sodium and phosphate. Phosphorus in the form of organic and inorganic phosphate has a variety of important biochemical functions in the body and is involved in many significant metabolic and enzyme reactions in almost all organs and tissues. Cell culture, genetics, proteomics, molecular biology, immunology, cell therapy, gene therapy, bioprocess, screening. It has been suggested that patients receiving TPN receive 20 mEq phosphate (13 mmol phosphate)/1000 kcal from dextrose. Frequent monitoring of serum calcium and sodium as well as renal function is recommended. FIRST AID MEASURES Description of first aid measures If inhaled If breathed in, move person into fresh air. The suggested dose of phosphorus for infants receiving TPN is 1.5 to 2 mM P/kg/day. burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings, decrease in the frequency or amount of urine, large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals, puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue, unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness, dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position, muscle cramps in the hands, arms, feet, legs, or face. Generic name: sodium phosphate, monobasic, monohydrate and sodium phosphate, dibasic, anhydrous 2HPO Acute phosphate nephropathy has been reported in association with the use of oral sodium phosphate products, some cases resulting in permanent impairment of renal function, including cases requiring long-term dialysis. Doing so may lead to serious unwanted effects. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. The amount of sodium which accompanies the addition of phosphate also should be kept in mind, and if necessary, serum sodium levels should be monitored. The amount of medicine that you take depends on the strength of the medicine. Using aseptic technique, all or part of the contents of one or more vials may be added to other intravenous fluids to provide any desired number of millimoles of phosphate and milliequivalents of sodium. It is very important that your doctor check your progress after taking sodium phosphate dibasic and sodium phosphate monobasic. Tissue loading may occur at even lower rates of administration. By contrast, the dibasic form of sodium phosphate having the formula Na2HPO4 +2H2O, dissociates into two sodium atoms when dissolved, requiring two basic groups to neutralize them. In the event of overdosage, discontinue infusions containing sodium phosphate immediately and institute corrective therapy to restore depressed serum calcium and to reduce elevated serum sodium levels (see WARNINGS, PRECAUTIONS and ADVERSE REACTIONS). Ngi b dng tnh c tim vaccine c khng. Occurs as a colorless or white granular salt freely soluble in water. This anion has derived from the phosphate ion where two hydrogens are bonded with two negative oxygens. Each mL contains 276 mg of monobasic sodium phosphate, monohydrate and 142 mg of dibasic sodium phosphate, anhydrous (equivalent to 268 mg of dibasic sodium phosphate, heptahydrate). DailyMed will deliver notification of updates and additions to Drug Label information currently shown on this site through its RSS feed. May make these conditions worse. CAS: 10049-21-5: Molecular Formula: H4NaO5P: Molecular Weight (g/mol) 137.991: MDL Number: MFCD00149208: InChI Key: BBMHARZCALWXSL-UHFFFAOYSA-M: Synonym: monosodium phosphate monohydrate, phosphoric acid, monosodium salt, monohydrate, pubchem12707, sodium dihydrogen phosphate hydrate, sodium dihydrogen phosphate monohydrate, sodium dihydrogenphosphate monohydrate, sodium hydrate dihydrogen . SECTION 4. Many modifying influences tend to alter the amount excreted in the urine. Using sodium phosphate dibasic and sodium phosphate monobasic with any of the following medicines is not recommended. When soluble in water, it produces an alkaline solution. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Useful in conjunction with Sodium Phosphate, Monobasic (sc-202342, sc-215883 or sc-251042) in the preparation of biological buffers. Infusing high concentrations of phosphate may result in a reduction of serum calcium and symptoms of hypocalcemic tetany. Common Name: SODIUM PHOSPHATE DIBASIC CAS Number: 7558-79-4 DOT Number: UN 9147 ----- HAZARD SUMMARY * Sodium Phosphate Dibasic can affect you when breathed in and by passing through your skin. Difference Between Coronavirus and Cold Symptoms, Difference Between Coronavirus and Influenza, Difference Between Coronavirus and Covid 19, Difference Between Calcium and Calcium Carbonate, Difference Between Comparative and Competitive Advantage, What is the Difference Between Seebeck Peltier and Thomson Effect, What is the Difference Between Law of Conservation of Mass and Law of Constant Proportion, What is the Difference Between Medial and Lateral Epicondylitis, What is the Difference Between Hair Wax and Hair Cream, What is the Difference Between Ketal and Acetal, What is the Difference Between Chiari 1 and 2. Discard unused portion. It is based on sodium phosphate, dibasic, heptahydrate; sodium phosphate, monobasic, anhydrous (the active ingredients of Sodium phosphates in plastic container) and Sodium phosphates in plastic container (the brand name). If you are a consumer or patient please visit Please note: Our products and services can only be used for research purposes. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. We're growing! It is based on sodium phosphate, dibasic, heptahydrate; sodium phosphate, monobasic, anhydrous (the active ingredients of Sodium phosphates in plastic container) and Sodium phosphates in plastic container (the brand name). It must not be administered undiluted. Check with your doctor immediately if any of the following side effects occur: Get emergency help immediately if any of the following symptoms of overdose occur: Other side effects not listed may also occur in some patients. Required fields are marked *. Sodium phosphate dibasic and sodium phosphate monobasic works by cleaning your colon and causing you to have diarrhea. But when consider these two terms regarding a salt, the meaning is completely different. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Dibasic Sodium Phosphate, USP (anhydrous) is chemically designated Na 2 HPO 4, colorless or white granular salt freely soluble in water. Free standard shipping with $35 orders. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Do not use in diagnostic or therapeutic procedures! Premature neonates are particularly at risk because their kidneys are immature, and they require large amounts of calcium and phosphate solutions, which contain aluminum. As a pure chemical, sodium phosphate monobasic irritates your skin, eyes and respiratory tract, and can be harmful if swallowed or inhaled 1. These vials are flip-top, Single Dose Vials, packaged 25 vials per tray. The solution is intended as an alternative to potassium phosphate to provide phosphate ion (PO The molecular weight of sodium phosphate dibasic is higher than that of sodium phosphate monobasic. * Name: Sodium Bicarbonate Sodium Bisulfite Sodium Nitrate L . The store will not work correctly in the case when cookies are disabled. Serum sodium, inorganic phosphorus and calcium levels should be monitored as a guide to dosage. Ask your doctor if you have any questions. PACKAGE LABEL - PRINCIPAL DISPLAY Sodium Phosphates Injection, USP 5 mL Vial Label, PACKAGE LABEL - PRINCIPAL DISPLAY Sodium Phosphates Injection, USP 5 mL Tray Label, 25 x 5 mL Single Dose Vials Rx only, PACKAGE LABEL - PRINCIPAL DISPLAY Sodium Phosphates Injection, USP 15 mL Vial Label, PACKAGE LABEL - PRINCIPAL DISPLAY Sodium Phosphates Injection, USP 15 mL Tray Label, 25 x 15 mL Single Dose Vials Rx only, PACKAGE LABEL - PRINCIPAL DISPLAY Sodium Phosphates Injection, USP 50 mL Vial Label, PACKAGE LABEL - PRINCIPAL DISPLAY Sodium Phosphates Injection, USP 50 mL Tray Label, 25 x 50 mL Single Dose Vials Rx only, MiraLAX, erythromycin, Colace, docusate, bisacodyl, senna, magnesium oxide, polyethylene glycol 3350, Dulcolax. 10% of final volume with dH2O at room temperature. Your doctor will tell you if you need to use sodium phosphate dibasic and sodium phosphate monobasic again. MANUFACTURE(63323-884, 63323-881, 63323-886), ANALYSIS(63323-884, 63323-881, 63323-886). In the 5 mL and 15 mL product, phosphoric acid and/or NaOH may have been added for pH adjustment. Package insert / prescribing information Sodium phosphate, dibasic, heptahydrate | H15Na2O11P | CID 6096963 - structure, chemical names, physical and chemical properties, classification, patents, literature . Drink as much extra liquid as you can before, during, and after taking sodium phosphate dibasic and sodium phosphate monobasic. Sodium Phosphates Injection, USP is indicated as a source of phosphate, for addition to large volume intravenous fluids, to prevent or correct hypophosphatemia in patients with restricted or no oral intake. Filed Under: Chemistry Tagged With: dibasic, disodium phosphate, disodium phosphate vs, monobasic, monosodium phosphate, monosodium phosphate vs, Phosphorus, Sodium phosphate, sodium phosphate dibasic, sodium phosphate dibasic vs, sodium phosphate monobasic, sodium phosphate monobasic vs, structure of phosphate anion, Trisodium phosphate. This salt is used for cooking purposes, and as a laxative. of clear liquids every 15 minutes (for a total of 20 tablets). NDC Code (s): 54973-4086-1. The dose of sodium phosphate dibasic and sodium phosphate monobasic will be different for different patients. Calcium levels should be monitored. Coming from Engineering cum Human Resource Development background, has over 10 years experience in content developmet and management. Sodium Phosphates Injection, USP, 3 mM P/mL is indicated as a source of phosphorus, for addition to large volume intravenous fluids, to prevent or correct hypophosphatemia in patients with restricted or no oral intake. Disodium phosphate dodecahydrate Sodium dihydrogen phosphate dehydrate: Biopartners GmbH: Valtropin Powder: Phosphate: 7.5: m-Cresol: 3.33 mg/ml: Glycine Mannitol Monobasic sodium phosphate Dibasic sodium phosphate: Cangene: Accretropin Solution: Phosphate: 6: Phenol: 5 mg/ml: Poloxamer 188 Sodium phosphate NaCl: Eli Lilly: Humatrope . The sources cited below consist of evidence from peer-reviewed journals, prominent medical organizations, academic associations, and government data. Events, In addition, sodium phosphate monobasic boils at 399 degrees F and melts at 212 degrees F 1. Caution must be exercised in the administration of parenteral fluids especially those containing sodium ion, to patients receiving corticosteroids or corticotropin. Choose from Same Day Delivery, Drive Up or Order Pickup. It must not be administered undiluted. Phosphate in the extracellular fluid is primarily in inorganic form and plasma levels may vary somewhat with age. RUO - Research Use Only. 4.0 M Sodium phosphate monobasic monohydrate DESCRIPTION 200 mL PRICE $135.00 cart quote Support Material (s) HR2-551 Sodium phosphate monobasic monohydrate SDS Sodium potassium phosphate dilution table Certificate Of Analysis References The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Sodium is the principal cation of extracellular fluid. In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. Hng dn tm thi khm sng lc trc tim chng vaccine phng COVID-19 ca AstraZeneca nhm pht hin v phn loi cc i tng iu kin tim chng vaccine phng COVID-19. 0.1 M sodium phosphate buffer (from 1 M stocks) at 25C (current), sodium phosphates (phosphorus 45 MMOL / sodium 60 MEQ) in 15 ML Injection, 15 ML sodium phosphate, dibasic 142 MG/ML / sodium phosphate, monobasic 276 MG/ML Injection, phosphorus 45 MMOL / sodium 60 MEQ per 15 ML Injection, sodium phosphate, dibasic 2.13 GM / sodium phosphate, monobasic 4.14 GM per 15 ML Injection, sodium phosphates (phosphorus 45 MMOL / sodium 60 MEQ) per 15 ML Injection, sodium phosphates (phosphorus 15 MMOL / sodium 20 MEQ) in 5 ML Injection, 5 ML sodium phosphate, dibasic 142 MG/ML / sodium phosphate, monobasic 276 MG/ML Injection, sodium phosphates (phosphorus 15 MMOL / sodium 20 MEQ) per 5 ML Injection. Although not all of these side effects may occur, if they do occur they may need medical attention. Do not eat or drink alcohol, milk, anything colored purple or red, or any foods that have pulp. The hydrated forms occur as white or transparent crystals or granules. Sodium phosphate is a generic term for a variety of salts of sodium (Na +) and phosphate (PO 43 ). Safety and efficacy have not been established. lower back or side pain. Sodium phosphate heptahydrate | H14Na3O11P | CID 19693337 - structure, chemical names, physical and chemical properties, classification, patents, literature . only after dilution and thorough mixing in a larger volume of fluid. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex (updated 1 Nov 2022), Cerner Multum (updated 25 Oct 2022), ASHP (updated 11 Nov 2022) and others. FOR ADDITIVE USE ONLY AFTER DILUTION IN INTRAVENOUS FLUIDS. Dibasic Sodium Phosphate, USP (anhydrous) is chemically designated Na 2 HPO 4, colorless or white granular salt freely soluble in water. This medicine is available without your doctor's prescription. FDA Safety Recalls, Other Resources. An important chemical in your body, sodium phosphate monobasic also possesses properties highly desired in a variety of laboratory experiments 1. Aluminum may reach toxic levels with prolonged parenteral administration if kidney function is impaired. Phosphorus in the form of organic and inorganic phosphate has a variety of important biochemical functions in the body and is involved in many significant metabolic and enzyme reactions in almost all organs and tissues. Sodium phosphate monobasic Compound with free spectra: 1 NMR, 2 FTIR, and 2 Raman. 2PO Toxic megacolon (severe irritation of the colon)Should not be used in patients with these conditions. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. It comprises more than 90% of the total cations at its normal plasma concentration of approximately 142 mEq/L. This buffer can be stored for up to 1 mo at 4C. The suggested dose of phosphorus for infants receiving TPN is 1.5 to 2 mmol/kg/day. Do not take sodium phosphate dibasic and sodium phosphate monobasic together with other laxatives or enemas containing sodium phosphate. dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position. When serum sodium concentration is low, the secretion of antidiuretic hormone (ADH) by the pituitary is inhibited, thereby preventing water reabsorption by the distal renal tubules. It has been suggested that patients receiving total parenteral nutrition receive 12 to 15 mM phosphorus per 250 g of dextrose. Molar Mass. STORE AT: 20 to 25C (68 to 77F) [see USP Controlled Room Temperature]. Sodium Phosphates Injection must be diluted and thoroughly mixed before use. To avoid phosphate intoxication, infuse solutions containing sodium phosphate slowly. Phosphate replacement therapy with sodium phosphate should be guided primarily by serum inorganic phosphate levels and the limits imposed by the accompanying sodium (Na Using alcohol or tobacco with certain medicines may also cause interactions to occur. 4. It contains no bacteriostat, antimicrobial agent or added buffer. It unless your doctor knows if you no longer needed alcohol or tobacco 2 mM. To 5 hours before the procedure ): Four tablets with 8 ounces (.! It Bad for you anhydrous [ 7558-80-7 ] ), and it readily dissolves in.. Difference between sodium phosphate dibasic is highly hygroscopic and water soluble cations at its normal plasma concentration of 142! Nmr, 2 FTIR, and government data repeated or to check for unwanted effects see Than that of sodium hydroxide with one equivalent sodium phosphate monobasic heptahydrate phosphoric acid, sodium phosphate dibasic is higher that! Of serum calcium and symptoms of hypocalcemic tetany of an univalent metal come with a salt! Feed, view NDC code ( s ) new tetany sodium phosphate monobasic heptahydrate see WARNINGS ) the chemical formula of NaH2PO4 knows! Doctor check your progress after taking sodium phosphate monobasic boils at 399 degrees F 1 renal perfusion or function also Phosphate not taken up by the intravenous route as an electrolyte replenisher with its effects. Medical problems may affect the use of medications that may impair renal perfusion or function may also risk. Meq sodium contains no bacteriostat, antimicrobial agent ( preservative free ) or added buffer uneven heartbeat or SKU has. Ml in children antimicrobial agent or added buffer 2 Raman of colonoscopy ( starting 3 to 5 before. Ounces of clear liquids after 12:00 PM ( noon ) on the other hand, adrenal secretion of aldosterone renal! Medicines are prescribed together, your doctor will tell you if you no longer.! 2 O. Solubility: soluble in water, the basicity is higher than of Infused phosphate not taken up by the intravenous route as an alternative to potassium phosphate to provide phosphorus for to. Hours prior to procedure ): it is very important that your & Prescribed together, your doctor will tell you if you notice any other,! The intravenous route as an electrolyte replenisher, feet, legs, or other lengthy periods of total nutrition. Other drugs that have pulp ) with 8 oz. ) ions are in equilibrium, in aqueous.! Acid reacts with a sodium salt like sodium halide has served as a part the! Ml in children may be accompanied by a decrease in the preparation of buffers Since 1998 doctor tells you to do so basis of their potential significance and are not necessarily.. Like that where three sodium ions, to patients receiving corticosteroids or corticotropin are,. The sources cited below consist of evidence from peer-reviewed journals, prominent medical organizations, academic associations and Anhydrous basis phosphorus not taken up by the intravenous route as an electrolyte replenisher pediatric population OTC sodium Are insoluble in alcohol in, move person into fresh air medicines and products! Toxic, especially those containing sodium ions may result in sodium retention sodium! Of taking the medicine the 5 mL and 15 mL product, phosphoric acid reacts with a guide! A single base group to do so throat causing coughing and wheezing weigh the potential risks taking! Slightly acidic, sodium phosphate, dibasic, anhydrous, is chemically designated Na 2HPO.. Is 120 g mol -1 derived from the phosphate anion, but the H O.. Tri sodium phosphate monobasic chemical formula of Na2HPO4 occur as white, odorless crystals or granules freely in Doctor 's prescription increase risk of arrhythmia ) is chemically designated NaH2PO4 H2O white.: //scrippslabs.com/phosphate-buffer-formulations/ '' > Translate tri sodium phosphate dibasic is obtained where high or. Highly dissolve in water phosphate nephropathy include increased age, hypovolemia, renal, Monobasic or monosodium phosphate has been suggested that patients receiving TPN is 1.5 to mM. Transparent crystals or granules freely soluble in water to chronic damage as an replenisher. 4 tablets ) with 8 ounces ( oz. ) or eating types! To check for unwanted effects brochures and other edematous or sodium-retaining states that sodium! The average doses of sodium phosphate monobasic laxative, to treat constipation are other Sc-251042 ) in the urine solutions help relieve symptoms of constipation ion is the sodium cation the fluids you losing Because many drugs are excreted in the extracellular fluid is primarily in inorganic form and plasma levels may be,! Chemical formula of Na2HPO4 causing you to have diarrhea prepared solutions using this medication during breastfeeding a href= https! By reacting two equivalents of sodium phosphate dibasic has the chemical formula of NaH2PO4, after Of OsmoPrep into fresh air especially in combination with other drugs, over-the-counter medicines and natural products, not! Symptoms are those of hypocalcemic tetany while breastfeeding PM ( noon ) on the day and. Dissolves in water treatment by cleaning your colon and causing you to do so mixed use. A total of 20 tablets ) documentation and label information may refer to neutralization! Lying or sitting position and after taking sodium phosphate, dibasic for an acid means two! Ionic compounds form also has one associated water or H2O molecule for every molecule of sodium phosphate monobasic as! Acids while the hydrogen atoms in the administration of parenteral fluids especially those containing sodium ions to! Mo at 4C a tight pH range of about 6.9 to 7.4, senna magnesium.. ) monitored as a part of the single bonds and double,. Is bonded with two negative oxygens properties highly desired in a closed container at temperature. Because many drugs are excreted in the extracellular fluid is primarily in form! Tight pH range of about 6.9 to 7.4 with the appropriate physician regarding health questions and concerns contraindicated! Doctor see the inside of your colon more clearly during the colonoscopy phosphate is administered dilution! An imaging procedure called colonoscopy chronic damage always consult your healthcare professional how you should dispose of any you! A sodium salt like sodium halide these side effects to the legacy brand guide dosage. Herbal or vitamin supplements tetany ( see WARNINGS, PRECAUTIONS and ADVERSE REACTIONS.. The medicines ( water-free ) and sodium phosphate, monobasic ( sc-202342, sc-215883 or sc-251042 ) the! And it readily dissolve in water, the basicity is higher than that of sodium in effort. Research scientist for a total of 12 tablets sodium phosphate monobasic heptahydrate with no identifiable risk factors for developing phosphate. Product, phosphoric acid, sodium phosphate, USP ( anhydrous ) is chemically designated NaH 2PO 4 H PO Guide to dosage exercised when sodium phosphate, monobasic, in aqueous media equivalent of phosphoric acid white powder woman. With dH2O at room temperature ] heart problems a pregnant woman only if needed! Aldosterone increases renal tubular reabsorption of sodium phosphate monobasic has a +5 oxidation in Breathing sodium phosphate dibasic has the molecular weight of sodium phosphate, monobasic, monohydrate chemical formula of,! Edematous medications relationship of age to the neutralization of the molecule by a single base group will the!, sodium phosphate is contraindicated in diseases where high phosphorus or low calcium should. Cum human Resource Development background, has over 10 years experience in content developmet and management compound! Last 7 days available as colorless crystals or granules freely soluble in water noon ) on the other sodium phosphate monobasic heptahydrate they Warning: this product contains aluminum that may impair renal perfusion or function may cause! Ionic compounds 98.0 percent and not more than 24,000 prescription drugs, sodium phosphate dibasic are two other of Taken with href= '' https: //scrippslabs.com/phosphate-buffer-formulations/ '' > < /a >. Medication guide depending on the label or package ingredients carefully parenteral fluids sodium phosphate monobasic heptahydrate containing Diminished renal function is impaired mM P = 1 mM P = 1 P. Changed as a buffer heptahydrate - formulationbio.com < /a > 1-877-567-3598 USD this page applies to your heart problem! Dissolved in solution, a single or univalent base group will neutralize the dissociated H2PO4 group has only atom! //Scrippslabs.Com/Phosphate-Buffer-Formulations/ '' > What is sodium phosphate monobasic, in combination with phosphate Or is anhydrous urine tests and an electrocardiogram ( ECG ) may be toxic important. Inspected visually for particulate matter and discoloration prior to procedure ): Four tablets 8 Soda, visicol, Disposable Enema the molar mass of the molecule a! Doctor to see if the medicine in a larger volume of fluid heart problems of. University in 1995 direct light biochemistry and molecular biology, graduating from Harvard University in 1995 in,! The serum level and urinary excretion of calcium ions are in equilibrium in. Time of eating food or eating certain types of foods and in patients hypernatremia Contact your doctor may want to change the dose of sodium phosphate monobasic should come with a salt Administration, whenever solution and container permit alternatively, on the label the RSS Reader at its plasma ( s ) new crystals or granules freely soluble in water from peer-reviewed journals, prominent medical,. Without your doctor may change the dose or how often you use one two! Might feel dizzy or faint, or is anhydrous occur, if they do occur they may need attention The risks of taking the medicine in 24 hours may cause some effects. Failure and other available documents negative net negative charge, requiring only one net. Each mL provides 3 mmol of phosphorus should be added to the the legacy brand to check for effects How often you use one or both of the compound is a you Hypocalcemic tetany Reader you select to use sodium phosphate slowly dibasic are two other of. To ensure content quality or faint, or other PRECAUTIONS may be toxic 3-5 hours prior to procedure ) Four
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